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Important information about Revatio



Important information about Revatio
Revatio (sildenafil) relaxes muscles and increases blood flow to particular areas of the body.
Revatio is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women. Sildenafil under the brand name Viagra is used to treat erectile dysfunction (impotence) in men. Do not take Viagra while also taking Revatio, unless your doctor tells you to.

Revatio may also be used for other purposes not listed in this medication guide.

Important information about Revatio

Do not take Revatio if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket). Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking Revatio with a nitrate medicine can cause a sudden and serious decrease in blood pressure. During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of Revatio. Do not take Revatio more than once a day. Allow 24 hours to pass between doses. Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Revatio can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Revatio, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether Revatio is the actual cause of vision loss.

Stop using Revatio and get emergency medical help if you have sudden vision loss.

What should I discuss with my healthcare provider before taking Revatio?

Do not take Revatio if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, and others), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket). Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking Revatio with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.

To make sure you can safely take Revatio, tell your doctor if you have any of these other conditions:

heart disease or heart rhythm problems;
a recent history (in the past 6 months) of a heart attack, stroke, or congestive heart failure;
high or low blood pressure;
coronary artery disease;
liver disease;
kidney disease;
a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
a bleeding disorder such as hemophilia;
a stomach ulcer;
retinitis pigmentosa (an inherited condition of the eye);
a physical deformity of the penis (such as Peyronie's disease); or
if you have been told you should not have sexual intercourse for health reasons.
If you have any of these conditions, you may need a dose adjustment or special tests to safely take Revatio.

Revatio can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Revatio, most of whom also had heart disease, diabetes, high blood pressure, high cholesterol, or certain pre-existing eye problems, and in those who smoke or are over 50 years old. It is not clear whether Revatio is the actual cause of vision loss. Stop using Revatio and get emergency medical help if you have sudden vision loss.
FDA pregnancy category B: This medication is not expected to be harmful to an unborn baby. Do not use Revatio without telling your doctor if you are pregnant or plan to become pregnant during treatment. It is not known if Revatio passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.